The main active ingredient of the artichoke is cynarine (1,5-dicaffeylquinic acid), a substance that stimulates the production of bile, and hence renders the artichoke an excellent starter for any meal. This is yet another example of science finding a logical reason for people eating artichokes for centuries in order to promote the health of their liver and digestive system. It is not only for its cynarine content that the globe artichoke is useful, however, but also the luteolin and chlorogenic acids that it contains.The stimulation of bile production by the cynarine is one the more important of the effects of artichoke on your well being. Bile emulsifies fats and renders them into an easily digested form. Most of the digestive chemicals are water soluble, and without this emulsification of the fat with water then most of the fats we consume would pass through the body unchanged. We would the vats majority of the fat soluble nutrients in our food, including vitamins A, D, E and K.
Bile enables us to digest fats and to absorb vitamins from our food, and also promotes the general health of our digestive system. It is biosynthesized in the liver from various enzymes and triglycerides and then stored in the gall bladder until needed. Its use is prompted by the presence of fats in the system, and this is stimulated by the cynarine in the artichoke leaves.
Its ability to improve bile flow has been recognized by scientist’s world wide, and artichoke juice has been used by the French for many years as a liver tonic. However, it is not just for the liver and the digestive system that artichokes are useful in maintaining good health. They also have an effect on the cholesterol levels in your blood. This is believed to be due to the inhibition of the activity of enzyme HMG CoA Reductase that helps the liver to generate cholesterol. Inhibiting the activity of this enzyme reduces the amount of cholesterol produced.

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